31. this chart shows the significance of the primary structure of amino acids. why was the one amino acid…

31. this chart shows the significance of the primary structure of amino acids. why was the one amino acid different between normal hemoglobin and sickle cell hemaglobin?

31. this chart shows the significance of the primary structure of amino acids. why was the one amino acid different between normal hemoglobin and sickle cell hemaglobin?

Answer

Brief Explanations:

Sickle - cell anemia is a genetic disorder. A single - base mutation in the DNA that codes for hemoglobin leads to a change in the primary structure of the protein. This mutation causes a substitution of one amino acid (valine instead of glutamic acid) in the beta - globin chain of hemoglobin. This change in amino acid affects the shape and function of the hemoglobin molecule, causing red blood cells to sickle.

Answer:

A single - base DNA mutation led to an amino - acid substitution.