3. describe how a faulty protein alters the movement of chloride ions across the cell membrane. how does…

3. describe how a faulty protein alters the movement of chloride ions across the cell membrane. how does this change in the cell membrane lead to the symptoms of cystic fibrosis?

3. describe how a faulty protein alters the movement of chloride ions across the cell membrane. how does this change in the cell membrane lead to the symptoms of cystic fibrosis?

Answer

Brief Explanations:

In cystic fibrosis, the faulty protein is the cystic - fibrosis transmembrane conductance regulator (CFTR). Normally, CFTR acts as a channel protein to allow chloride ions to move out of cells. When it is faulty, chloride ion movement is impaired. This leads to an imbalance in the movement of water across the cell membrane via osmosis. With less chloride out, less water follows, resulting in thick, sticky mucus production. This mucus clogs the lungs, leading to respiratory problems, and also affects the pancreas, causing digestive issues.

Answer:

The faulty CFTR protein impairs chloride ion movement out of cells. This disrupts osmotic water movement, causing thick mucus production which leads to respiratory and digestive symptoms of cystic fibrosis.