which issue is related to long - term cocaine use?\no mental alertness\no paranoia\no extreme happiness\no…

Brief Explanations:

Long - term cocaine use can cause a variety of psychological problems. Paranoia is a well - known psychological effect associated with long - term cocaine use. Mental alertness may initially seem to increase with cocaine use but is not a long - term positive or typical related issue. Extreme happiness is a short - term high, not a long - term related issue. Sensitivity to light is not a common long - term issue related to cocaine use.

Answer:

paranoia