a nurse is speaking to a client who is taking sertraline and reports drinking grapefruit juice. the nurse…

a nurse is speaking to a client who is taking sertraline and reports drinking grapefruit juice. the nurse explains that grapefruit juice inhibits an enzyme in the liver that is used to metabolize sertraline. the nurse should recognize the clients risk for which of the following?\n\nreduced medication absorption\n\nmedication dependence\n\naltered medication distribution\n\nmedication toxicity

a nurse is speaking to a client who is taking sertraline and reports drinking grapefruit juice. the nurse explains that grapefruit juice inhibits an enzyme in the liver that is used to metabolize sertraline. the nurse should recognize the clients risk for which of the following?\n\nreduced medication absorption\n\nmedication dependence\n\naltered medication distribution\n\nmedication toxicity

Answer

Brief Explanations:

When grapefruit juice inhibits the liver enzyme that metabolizes sertraline, the drug is not broken down as effectively. This leads to higher levels of sertraline in the body, increasing the risk of medication toxicity. Reduced absorption would be about getting less into the body initially, dependence is about psychological/physical need, and distribution is about where the drug goes, not accumulation from inhibited metabolism.

Answer:

Medication toxicity