a pharmacy technician should identify that which of the following over - the - counter (otc) medications is…

a pharmacy technician should identify that which of the following over - the - counter (otc) medications is most likely to increase a patients risk for gastrointestinal (gi) bleeding?\nacetaminophen (tylenol)\nfamotidine (pepcid)\nibuprofen (motrin)\ndiphenhydramine (benadryl)
Answer
Brief Explanations:
- Acetaminophen (Tylenol) is mainly associated with liver toxicity when misused, not GI bleeding.
- Famotidine (Pepcid) is a histamine - 2 receptor antagonist that reduces stomach acid, which helps protect the GI mucosa rather than increasing bleeding risk.
- Ibuprofen (Motrin) is a non - steroidal anti - inflammatory drug (NSAID). NSAIDs can inhibit cyclooxygenase (COX) enzymes. COX - 1 is important for maintaining the integrity of the gastric mucosa (by promoting the production of prostaglandins that protect the stomach lining). Inhibiting COX - 1 with NSAIDs like ibuprofen can lead to gastric mucosal damage and increase the risk of GI bleeding.
- Diphenhydramine (Benadryl) is an anti - histamine. Its main side - effects are related to sedation, anticholinergic effects (such as dry mouth, blurred vision) rather than GI bleeding.
Answer:
C. Ibuprofen (Motrin)