select the correct answer.\nchronic myeloid leukemia (cml) is a genetic disorder associated with the…

select the correct answer.\nchronic myeloid leukemia (cml) is a genetic disorder associated with the philadelphia chromosome. the philadelphia chromosome is a mutation in chromosome 22. part of chromosome 22 is exchanged with part of chromosome 9, bringing together two genes on chromosome 22 and causing a malignancy. what type of mutation occurs in the philadelphia chromosome?\na. duplication\nb. insertion\nc. inversion\nd. substitution\ne. translocation

select the correct answer.\nchronic myeloid leukemia (cml) is a genetic disorder associated with the philadelphia chromosome. the philadelphia chromosome is a mutation in chromosome 22. part of chromosome 22 is exchanged with part of chromosome 9, bringing together two genes on chromosome 22 and causing a malignancy. what type of mutation occurs in the philadelphia chromosome?\na. duplication\nb. insertion\nc. inversion\nd. substitution\ne. translocation

Answer

Brief Explanations:

Translocation is a type of chromosomal mutation where a segment of one chromosome breaks off and attaches to a non - homologous chromosome. In the case of the Philadelphia chromosome, part of chromosome 22 is exchanged with part of chromosome 9, which is a translocation event. Duplication involves the repetition of a segment within a chromosome, insertion is the addition of extra DNA, inversion is the reversal of a segment within a chromosome, and substitution is a point - mutation at the nucleotide level, none of which describe the Philadelphia chromosome mutation.

Answer:

E. translocation