which statement best explains the relationship between hbs allele frequency and malaria endemicity in…

which statement best explains the relationship between hbs allele frequency and malaria endemicity in africa?\nwhen an area is malaria free, the hbs allele frequency is between 0 and 4.04.\nwhen an area is holoendemic, the hbs allele frequency is between 0.52 and 4.04.\nwhen an area is malaria free, the hbs allele frequency is between 12.64 and 18.18.\nwhen an area is holoendemic, the hbs allele frequency is between 0 and 0.51.
Answer
Answer:
When an area is malaria - free, the HbS allele frequency is between 0 and 4.04.
Explanation:
Step1: Comprender la resistencia al paludismo
Los portadores heterocigotos del alelo HbS tienen resistencia al paludismo.
Step2: Analizar las frecuencias en áreas libres de paludismo
En áreas donde no hay paludismo, no hay presión selectiva positiva por el alelo HbS, por lo que su frecuencia es baja, entre 0 y 4.04.