which statement best explains the relationship between hbs allele frequency and malaria endemicity in…

which statement best explains the relationship between hbs allele frequency and malaria endemicity in africa?\no when an area is malaria free, the hbs allele frequency is between 0 and 4.04.\no when an area is holoendemic, the hbs allele frequency is between 0.52 and 4.04.\no when an area is malaria free, the hbs allele frequency is between 12.64 and 18.18.\no when an area is holoendemic, the hbs allele frequency is between 0 and 0.51.

which statement best explains the relationship between hbs allele frequency and malaria endemicity in africa?\no when an area is malaria free, the hbs allele frequency is between 0 and 4.04.\no when an area is holoendemic, the hbs allele frequency is between 0.52 and 4.04.\no when an area is malaria free, the hbs allele frequency is between 12.64 and 18.18.\no when an area is holoendemic, the hbs allele frequency is between 0 and 0.51.

Answer

Answer:

When an area is malaria - free, the HbS allele frequency is between 0 and 4.04.

Explanation:

Step1: Understand malaria - HbS relationship

The HbS allele (sickle - cell allele) provides some resistance to malaria. In malaria - free areas, there is no selective advantage for the HbS allele, so its frequency is low.

Step2: Analyze options

In malaria - free areas, the frequency of the HbS allele is indeed low, typically between 0 and 4.04. Holoendemic areas have a high prevalence of malaria, and the HbS allele frequency is higher in such areas due to the selective advantage it provides against malaria. So the other options about holoendemic areas and the incorrect frequency ranges for malaria - free areas are wrong.